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LGP2 virus sensor enhances apoptosis by upregulating apoptosis regulatory genes through TRBP-bound miRNAs during viral infection

During viral infection, viral nucleic acids are detected by virus sensor proteins including toll-like receptor 3 or retinoic acid-inducible gene I-like receptors (RLRs) in mammalian cells. Activation of these virus sensor proteins induces type-I interferon production and represses viral replication....

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Detalles Bibliográficos
Autores principales: Takahashi, Tomoko, Nakano, Yuko, Onomoto, Koji, Yoneyama, Mitsutoshi, Ui-Tei, Kumiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7026649/
https://www.ncbi.nlm.nih.gov/pubmed/31799626
http://dx.doi.org/10.1093/nar/gkz1143