Cargando…
LGP2 virus sensor enhances apoptosis by upregulating apoptosis regulatory genes through TRBP-bound miRNAs during viral infection
During viral infection, viral nucleic acids are detected by virus sensor proteins including toll-like receptor 3 or retinoic acid-inducible gene I-like receptors (RLRs) in mammalian cells. Activation of these virus sensor proteins induces type-I interferon production and represses viral replication....
Autores principales: | Takahashi, Tomoko, Nakano, Yuko, Onomoto, Koji, Yoneyama, Mitsutoshi, Ui-Tei, Kumiko |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7026649/ https://www.ncbi.nlm.nih.gov/pubmed/31799626 http://dx.doi.org/10.1093/nar/gkz1143 |
Ejemplares similares
-
LGP2 virus sensor regulates gene expression network mediated by TRBP-bound microRNAs
por: Takahashi, Tomoko, et al.
Publicado: (2018) -
Virus Sensor RIG-I Represses RNA Interference by Interacting with TRBP through LGP2 in Mammalian Cells
por: Takahashi, Tomoko, et al.
Publicado: (2018) -
Interactions between the non-seed region of siRNA and RNA-binding RLC/RISC proteins, Ago and TRBP, in mammalian cells
por: Takahashi, Tomoko, et al.
Publicado: (2014) -
Viral RNA recognition by LGP2 and MDA5, and activation of signaling through step-by-step conformational changes
por: Duic, Ivana, et al.
Publicado: (2020) -
Structural characterization of the ANTAR antiterminator domain bound to RNA
por: Walshe, James L, et al.
Publicado: (2022)