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Central Actions of 3α,5α-THP Involving NMDA and GABA(A) Receptors Regulate Affective and Sexual Behavior of Female Rats

The neurosteroid, 5α-pregnan-3α-ol-20-one (known as “allopregnanolone” or 3α,5α-THP), is produced in the midbrain ventral tegmental area (VTA), independent of peripheral sources of progestogens, where it has potential actions at N-methyl-D-aspartate (NMDA) and GABA(A) receptors to facilitate rodent...

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Detalles Bibliográficos
Autores principales: Frye, Cheryl A., Qrareya, Alaa, Llaneza, Danielle C., Paris, Jason J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7026732/
https://www.ncbi.nlm.nih.gov/pubmed/32116591
http://dx.doi.org/10.3389/fnbeh.2020.00011