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SPECS: a non-parametric method to identify tissue-specific molecular features for unbalanced sample groups

BACKGROUND: To understand biology and differences among various tissues or cell types, one typically searches for molecular features that display characteristic abundance patterns. Several specificity metrics have been introduced to identify tissue-specific molecular features, but these either requi...

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Detalles Bibliográficos
Autores principales: Everaert, Celine, Volders, Pieter-Jan, Morlion, Annelien, Thas, Olivier, Mestdagh, Pieter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7026976/
https://www.ncbi.nlm.nih.gov/pubmed/32066370
http://dx.doi.org/10.1186/s12859-020-3407-z