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Prospective isolation of chondroprogenitors from human iPSCs based on cell surface markers identified using a CRISPR-Cas9-generated reporter

BACKGROUND: Articular cartilage shows little or no capacity for intrinsic repair, generating a critical need of regenerative therapies for joint injuries and diseases such as osteoarthritis. Human-induced pluripotent stem cells (hiPSCs) offer a promising cell source for cartilage tissue engineering...

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Detalles Bibliográficos
Autores principales: Dicks, Amanda, Wu, Chia-Lung, Steward, Nancy, Adkar, Shaunak S., Gersbach, Charles A., Guilak, Farshid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7026983/
https://www.ncbi.nlm.nih.gov/pubmed/32070421
http://dx.doi.org/10.1186/s13287-020-01597-8