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CHD4/NuRD complex regulates complement gene expression and correlates with CD8 T cell infiltration in human hepatocellular carcinoma

BACKGROUNDS: The NuRD (Nucleosome Remodeling and Deacetylation) complex is a repressive complex in gene transcription by modulating chromatin accessibility of target genes to transcription factors and RNA polymerase II. Although individual subunits of the complex have been implicated in many other c...

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Detalles Bibliográficos
Autores principales: Shao, Simin, Cao, Haowei, Wang, Zhongkun, Zhou, Dongmei, Wu, Chaoshen, Wang, Shu, Xia, Dian, Zhang, Daoyong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7027061/
https://www.ncbi.nlm.nih.gov/pubmed/32070428
http://dx.doi.org/10.1186/s13148-020-00827-3