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Insulin-like growth factor-binding proteins play a significant role in the molecular response to imatinib in chronic myeloid leukemia patients

Imatinib (IM) is successfully used in the majority of patients with chronic myeloid leukemia (CML), but some patients develop resistance to drug treatment. Insufficient apoptosis results in uncontrolled cell proliferation, which is closely associated with the occurrence of drug resistance. Therefore...

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Detalles Bibliográficos
Autores principales: Ren, Yingli, Yin, Shihong, Lin, Ya, Xu, Xiucai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7027099/
https://www.ncbi.nlm.nih.gov/pubmed/32104232
http://dx.doi.org/10.3892/etm.2019.8364