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Pathway mapping of leukocyte transcriptome in influenza patients reveals distinct pathogenic mechanisms associated with progression to severe infection

BACKGROUND: Influenza infections produce a spectrum of disease severity, ranging from a mild respiratory illness to respiratory failure and death. The host-response pathways associated with the progression to severe influenza disease are not well understood. METHODS: To gain insight into the disease...

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Detalles Bibliográficos
Autores principales: Zerbib, Yoann, Jenkins, Emily K., Shojaei, Maryam, Meyers, Adrienne F. A., Ho, John, Ball, T. Blake, Keynan, Yoav, Pisipati, Amarnath, Kumar, Aseem, Kumar, Anand, Nalos, Marek, Tang, Benjamin M., Schughart, Klaus, McLean, Anthony
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7027223/
https://www.ncbi.nlm.nih.gov/pubmed/32066441
http://dx.doi.org/10.1186/s12920-020-0672-7