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The paradox of cancer genes in non-malignant conditions: implications for precision medicine

Next-generation sequencing has enabled patient selection for targeted drugs, some of which have shown remarkable efficacy in cancers that have the cognate molecular signatures. Intriguingly, rapidly emerging data indicate that altered genes representing oncogenic drivers can also be found in sporadi...

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Detalles Bibliográficos
Autores principales: Adashek, Jacob J., Kato, Shumei, Lippman, Scott M., Kurzrock, Razelle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7027240/
https://www.ncbi.nlm.nih.gov/pubmed/32066498
http://dx.doi.org/10.1186/s13073-020-0714-y