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Uric acid induced hepatocytes lipid accumulation through regulation of miR-149-5p/FGF21 axis

BACKGROUND: Hyperuricemia is a major risk for non-alcoholic fatty liver disease. However, the mechanisms for this phenomenon are not fully understood. This study aimed to investigate whether microRNAs mediated the pathogenic effects of uric acid on non-alcoholic fatty liver disease. METHODS: Microar...

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Detalles Bibliográficos
Autores principales: Chen, Shenghui, Chen, Dan, Yang, Hua, Wang, Xinyu, Wang, Jinghua, Xu, Chengfu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7027271/
https://www.ncbi.nlm.nih.gov/pubmed/32070295
http://dx.doi.org/10.1186/s12876-020-01189-z