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Low expression and hypermethylation of FOXP3 in regulatory T cells are associated with asthma in children

The aim of the present study was to determine the expression and methylation levels of forkhead transcription factor P3 (FOXP3) in peripheral blood CD4(+)CD25(+) regulatory T cells (Tregs) harvested from children with asthma, and to explore the pathogenesis of asthma. The percentages of CD4(+)CD25(+...

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Detalles Bibliográficos
Autores principales: Zhu, Xiaohua, Chen, Qiang, Liu, Zhiqiang, Luo, Daya, Li, Lan, Zhong, Ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7027311/
https://www.ncbi.nlm.nih.gov/pubmed/32104264
http://dx.doi.org/10.3892/etm.2020.8443