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Comprehensive Molecular Profiling for Relapsed/Refractory Pediatric Burkitt Lymphomas—Retrospective Analysis of Three Real-Life Clinical Cases—Addressing Issues on Randomization and Customization at the Bedside

In order to identify reasons for treatment failures when using targeted therapies, we have analyzed the comprehensive molecular profiles of three relapsed, poor-prognosis Burkitt lymphoma cases. All three cases had resembling clinical presentation and histology and all three patients relapsed, but t...

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Detalles Bibliográficos
Autores principales: Polaskova, Kristyna, Merta, Tomas, Martincekova, Alexandra, Zapletalova, Danica, Kyr, Michal, Mazanek, Pavel, Krenova, Zdenka, Mudry, Peter, Jezova, Marta, Tuma, Jiri, Skotakova, Jarmila, Cervinkova, Ivana, Valik, Dalibor, Zdrazilova-Dubska, Lenka, Noskova, Hana, Pal, Karol, Slaby, Ondrej, Fabian, Pavel, Kozakova, Sarka, Neradil, Jakub, Veselska, Renata, Kanderova, Veronika, Hrusak, Ondrej, Freiberger, Tomas, Klement, Giannoula Lakka, Sterba, Jaroslav
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7027364/
https://www.ncbi.nlm.nih.gov/pubmed/32117783
http://dx.doi.org/10.3389/fonc.2019.01531