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The Effects of Dexmedetomidine in a Rat Model of Sepsis-Induced Lung Injury are Mediated Through the Adenosine Monophosphate-Activated Protein Kinase (AMPK)/Silent Information Regulator 1 (SIRT1) Pathway

BACKGROUND: This study aimed to investigate the effects of dexmedetomidine in a rat model of sepsis-induced lung injury and the role of the adenosine monophosphate-activated protein kinase (AMPK) gene and silent information regulator 1 (SIRT1) gene signaling pathway. MATERIAL/METHODS: Sixty 28-week-...

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Detalles Bibliográficos
Autores principales: Wang, Ronghui, Xie, Yongxiang, Qiu, Jiwei, Chen, Jueying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7027370/
https://www.ncbi.nlm.nih.gov/pubmed/32034118
http://dx.doi.org/10.12659/MSM.919213