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A Photo‐responsive Small‐Molecule Approach for the Opto‐epigenetic Modulation of DNA Methylation

Controlling the functional dynamics of DNA within living cells is essential in biomedical research. Epigenetic modifications such as DNA methylation play a key role in this endeavour. DNA methylation can be controlled by genetic means. Yet there are few chemical tools available for the spatial and t...

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Detalles Bibliográficos
Autores principales: Nguyen, Ha Phuong, Stewart, Sabrina, Kukwikila, Mikiembo N., Jones, Sioned Fôn, Offenbartl‐Stiegert, Daniel, Mao, Shiqing, Balasubramanian, Shankar, Beck, Stephan, Howorka, Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7027477/
https://www.ncbi.nlm.nih.gov/pubmed/30773767
http://dx.doi.org/10.1002/anie.201901139