Crucial Roles of Two Hydrated Mg(2+) Ions in Reaction Catalysis of the Pistol Ribozyme

Pistol ribozymes constitute a new class of small self‐cleaving RNAs. Crystal structures have been solved, providing three‐dimensional snapshots along the reaction coordinate of pistol phosphodiester cleavage, corresponding to the pre‐catalytic state, a vanadate mimic of the transition state, and the...

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Detalles Bibliográficos
Autores principales: Teplova, Marianna, Falschlunger, Christoph, Krasheninina, Olga, Egger, Michaela, Ren, Aiming, Patel, Dinshaw J., Micura, Ronald
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7027511/
https://www.ncbi.nlm.nih.gov/pubmed/31804735
http://dx.doi.org/10.1002/anie.201912522

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7027511/
https://www.ncbi.nlm.nih.gov/pubmed/31804735
http://dx.doi.org/10.1002/anie.201912522

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