Preclinical safety assessment of pathogen reduced red blood cells treated with amustaline and glutathione

BACKGROUND: The nucleic acid targeted pathogen reduction (PR) system utilizing amustaline (S‐303) and glutathione (GSH) is designed to inactivate blood‐borne pathogens and leukocytes in red blood cell concentrates (PR‐RBCC). Inactivation is attained after amustaline intercalates and forms covalent n...

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Detalles Bibliográficos
Autores principales: North, Anne K., Mufti, Nina, Sullivan, Theresa, Corash, Laurence
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2020
Materias:
Blood Components
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7027779/
https://www.ncbi.nlm.nih.gov/pubmed/31930533
http://dx.doi.org/10.1111/trf.15662

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7027779/
https://www.ncbi.nlm.nih.gov/pubmed/31930533
http://dx.doi.org/10.1111/trf.15662

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