The NEDD4‐1 E3 ubiquitin ligase: A potential molecular target for bortezomib sensitivity in multiple myeloma

E3 ubiquitin ligases primarily determine the substrate specificity of the ubiquitin‐proteasome system and play an essential role in the resistance to bortezomib in multiple myeloma (MM). Neural precursor cell‐expressed developmentally downregulated gene 4‐1 (NEDD4‐1, also known as NEDD4) is a foundi...

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Detalles Bibliográficos
Autores principales: Huang, Xi, Gu, Huiyao, Zhang, Enfan, Chen, Qingxiao, Cao, Wen, Yan, Haimeng, Chen, Jing, Yang, Li, Lv, Ning, He, Jingsong, Yi, Qing, Cai, Zhen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2019
Materias:
Molecular Cancer Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7027789/
https://www.ncbi.nlm.nih.gov/pubmed/31390487
http://dx.doi.org/10.1002/ijc.32615

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7027789/
https://www.ncbi.nlm.nih.gov/pubmed/31390487
http://dx.doi.org/10.1002/ijc.32615

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