Phenylalanine meta‐Hydroxylase: A Single Residue Mediates Mechanistic Control of Aromatic Amino Acid Hydroxylation

The rare nonproteinogenic amino acid, meta‐l‐tyrosine is biosynthetically intriguing. Whilst the biogenesis of tyrosine from phenylalanine is well characterised, the mechanistic basis for meta‐hydroxylation is unknown. Herein, we report the analysis of 3‐hydroxylase (Phe3H) from Streptomyces coerule...

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Detalles Bibliográficos
Autores principales: Grüschow, Sabine, Sadler, Joanna C., Sharratt, Peter J., Goss, Rebecca J. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Full Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7027792/
https://www.ncbi.nlm.nih.gov/pubmed/31318464
http://dx.doi.org/10.1002/cbic.201900320

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7027792/
https://www.ncbi.nlm.nih.gov/pubmed/31318464
http://dx.doi.org/10.1002/cbic.201900320

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