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Inherited cardiac diseases, pluripotent stem cells, and genome editing combined—the past, present, and future
Research on mechanisms underlying monogenic cardiac diseases such as primary arrhythmias and cardiomyopathies has until recently been hampered by inherent limitations of heterologous cell systems, where mutant genes are expressed in noncardiac cells, and physiological differences between humans and...
Autores principales: | van den Brink, Lettine, Grandela, Catarina, Mummery, Christine L., Davis, Richard P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley & Sons, Inc.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7027796/ https://www.ncbi.nlm.nih.gov/pubmed/31664757 http://dx.doi.org/10.1002/stem.3110 |
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