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P53 Mutant p53(N236S) Regulates Cancer-Associated Fibroblasts Properties Through Stat3 Pathway

BACKGROUND: Cancer-associated fibroblasts (CAFs) play important roles in cancer development and progression. Recent studies show that p53 plays a cell non-autonomous tumor-suppressive role to restrict tumor growth in CAFs. However, the role of p53 mutant in CAFs remains obscure. METHODS: In this stu...

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Detalles Bibliográficos
Autores principales: Liu, Qing, Yu, Biao, Tian, Yingbin, Dan, Juhua, Luo, Ying, Wu, Xiaoming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7027832/
https://www.ncbi.nlm.nih.gov/pubmed/32104002
http://dx.doi.org/10.2147/OTT.S229065