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Partial loss of actin nucleator actin‐related protein 2/3 activity triggers blebbing in primary T lymphocytes

T lymphocytes utilize amoeboid migration to navigate effectively within complex microenvironments. The precise rearrangement of the actin cytoskeleton required for cellular forward propulsion is mediated by actin regulators, including the actin‐related protein 2/3 (Arp2/3) complex, a macromolecular...

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Detalles Bibliográficos
Autores principales: Obeidy, Peyman, Ju, Lining A, Oehlers, Stefan H, Zulkhernain, Nursafwana S, Lee, Quintin, Galeano Niño, Jorge L, Kwan, Rain YQ, Tikoo, Shweta, Cavanagh, Lois L, Mrass, Paulus, Cook, Adam JL, Jackson, Shaun P, Biro, Maté, Roediger, Ben, Sixt, Michael, Weninger, Wolfgang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7028084/
https://www.ncbi.nlm.nih.gov/pubmed/31698518
http://dx.doi.org/10.1111/imcb.12304