CYP2B6*6 Genotype Specific Differences in Artemether‐Lumefantrine Disposition in Healthy Volunteers

Cytochrome P450 2B6 (CYP2B6) is involved in the metabolism of the antimalarial drugs artemether and lumefantrine. Here we investigated the effect of CYP2B6*6 on the plasma pharmacokinetics of artemether, lumefantrine, and their metabolites in healthy volunteers. Thirty healthy and previously genotyp...

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Detalles Bibliográficos
Autores principales: Abdullahi, Sa'ad T., Soyinka, Julius O., Olagunju, Adeniyi, Bolarinwa, Rahman A., Olarewaju, Olusola J., Bakare‐Odunola, Moji T., Winterberg, Markus, Tarning, Joel, Owen, Andrew, Khoo, Saye
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Pharmacogenomics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7028104/
https://www.ncbi.nlm.nih.gov/pubmed/31549442
http://dx.doi.org/10.1002/jcph.1527

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7028104/
https://www.ncbi.nlm.nih.gov/pubmed/31549442
http://dx.doi.org/10.1002/jcph.1527

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