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Two‐day‐treatment of Activin‐A leads to transient change in SV‐HFO osteoblast gene expression and reduction in matrix mineralization

Activins regulate bone formation by controlling osteoclasts and osteoblasts. We investigated Activin‐A mechanism of action on human osteoblast mineralization, RNA and microRNA (miRNA) expression profile. A single 2‐day treatment of Activin‐A at Day 5 of osteoblast differentiation significantly reduc...

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Detalles Bibliográficos
Autores principales: Baroncelli, Marta, Drabek, Ksenija, Eijken, Marco, van der Eerden, Bram C. J., van de Peppel, Jeroen, van Leeuwen, Johannes P. T. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7028110/
https://www.ncbi.nlm.nih.gov/pubmed/31667867
http://dx.doi.org/10.1002/jcp.29365