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Selective reconstitution of IFN‑γ gene function in Ncr1(+) NK cells is sufficient to control systemic vaccinia virus infection

IFN-γ is an enigmatic cytokine that shows direct anti-viral effects, confers upregulation of MHC-II and other components relevant for antigen presentation, and that adjusts the composition and balance of complex cytokine responses. It is produced during immune responses by innate as well as adaptive...

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Detalles Bibliográficos
Autores principales: Borst, Katharina, Flindt, Sven, Blank, Patrick, Larsen, Pia-Katharina, Chhatbar, Chintan, Skerra, Jennifer, Spanier, Julia, Hirche, Christoph, König, Martin, Alanentalo, Tomas, Hafner, Martin, Waibler, Zoe, Pfeffer, Klaus, Sexl, Veronika, Sutter, Gerd, Müller, Werner, Graalmann, Theresa, Kalinke, Ulrich
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7028289/
https://www.ncbi.nlm.nih.gov/pubmed/32023327
http://dx.doi.org/10.1371/journal.ppat.1008279