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Synteny-based analyses indicate that sequence divergence is not the main source of orphan genes

The origin of ‘orphan’ genes, species-specific sequences that lack detectable homologues, has remained mysterious since the dawn of the genomic era. There are two dominant explanations for orphan genes: complete sequence divergence from ancestral genes, such that homologues are not readily detectabl...

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Detalles Bibliográficos
Autores principales: Vakirlis, Nikolaos, Carvunis, Anne-Ruxandra, McLysaght, Aoife
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7028367/
https://www.ncbi.nlm.nih.gov/pubmed/32066524
http://dx.doi.org/10.7554/eLife.53500