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Specific depletion of the motor protein KIF5B leads to deficits in dendritic transport, synaptic plasticity and memory

The kinesin I family of motor proteins are crucial for axonal transport, but their roles in dendritic transport and postsynaptic function are not well-defined. Gene duplication and subsequent diversification give rise to three homologous kinesin I proteins (KIF5A, KIF5B and KIF5C) in vertebrates, bu...

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Detalles Bibliográficos
Autores principales: Zhao, Junjun, Fok, Albert Hiu Ka, Fan, Ruolin, Kwan, Pui-Yi, Chan, Hei-Lok, Lo, Louisa Hoi-Ying, Chan, Ying-Shing, Yung, Wing-Ho, Huang, Jiandong, Lai, Cora Sau Wan, Lai, Kwok-On
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7028368/
https://www.ncbi.nlm.nih.gov/pubmed/31961321
http://dx.doi.org/10.7554/eLife.53456