Cargando…
Specific depletion of the motor protein KIF5B leads to deficits in dendritic transport, synaptic plasticity and memory
The kinesin I family of motor proteins are crucial for axonal transport, but their roles in dendritic transport and postsynaptic function are not well-defined. Gene duplication and subsequent diversification give rise to three homologous kinesin I proteins (KIF5A, KIF5B and KIF5C) in vertebrates, bu...
Autores principales: | Zhao, Junjun, Fok, Albert Hiu Ka, Fan, Ruolin, Kwan, Pui-Yi, Chan, Hei-Lok, Lo, Louisa Hoi-Ying, Chan, Ying-Shing, Yung, Wing-Ho, Huang, Jiandong, Lai, Cora Sau Wan, Lai, Kwok-On |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7028368/ https://www.ncbi.nlm.nih.gov/pubmed/31961321 http://dx.doi.org/10.7554/eLife.53456 |
Ejemplares similares
-
The epilepsy and intellectual disability-associated protein TBC1D24 regulates the maintenance of excitatory synapses and animal behaviors
por: Lin, Lianfeng, et al.
Publicado: (2020) -
Ketamine and selective activation of parvalbumin interneurons inhibit stress-induced dendritic spine elimination
por: Ng, Lhotse Hei Lui, et al.
Publicado: (2018) -
Dysregulation of protein synthesis and dendritic spine morphogenesis in ASD: studies in human pluripotent stem cells
por: Lo, Louisa Hoi-Ying, et al.
Publicado: (2020) -
Transplanting Human Neural Stem Cells with ≈50% Reduction of SOX9 Gene Dosage Promotes Tissue Repair and Functional Recovery from Severe Spinal Cord Injury
por: Liu, Jessica Aijia, et al.
Publicado: (2023) -
KIF24 depletion induces clustering of supernumerary centrosomes in PDAC cells
por: Mashima, Yu, et al.
Publicado: (2022)