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Delayed inhibition mechanism for secondary channel factor regulation of ribosomal RNA transcription

RNA polymerases (RNAPs) contain a conserved ‘secondary channel’ which binds regulatory factors that modulate transcription initiation. In Escherichia coli, the secondary channel factors (SCFs) GreB and DksA both repress ribosomal RNA (rRNA) transcription, but SCF loading and repression mechanisms ar...

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Detalles Bibliográficos
Autores principales: Stumper, Sarah K, Ravi, Harini, Friedman, Larry J, Mooney, Rachel Anne, Corrêa, Ivan R, Gershenson, Anne, Landick, Robert, Gelles, Jeff
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7028371/
https://www.ncbi.nlm.nih.gov/pubmed/30720429
http://dx.doi.org/10.7554/eLife.40576