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Interleukin-27 Enforces Regulatory T Cell Functions to Prevent Graft-versus-Host Disease

Graft-versus-host disease (GvHD) remains a significant complication of allogeneic hematopoietic cell transplantation (HCT), associated with significant morbidity and mortality. GvHD is characterized by dysregulated immune responses and resulting tissue damage of target organs. Recent investigations...

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Detalles Bibliográficos
Autores principales: Le, Hongnga T., Keslar, Karen, Nguyen, Quang Tam, Blazar, Bruce R., Hamilton, Betty K., Min, Booki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7028690/
https://www.ncbi.nlm.nih.gov/pubmed/32117306
http://dx.doi.org/10.3389/fimmu.2020.00181