Delivery of phosphatidylethanolamine blunts stress in hepatoma cells exposed to elevated palmitate by targeting the endoplasmic reticulum

Genetic obesity increases in liver phosphatidylcholine (PC)/phosphatidylethanolamine (PE) ratio, inducing endoplasmic reticulum (ER) stress without concomitant increase of ER chaperones. Here, it is found that exposing mice to a palm oil-based high fat (HF) diet induced obesity, loss of liver PE, an...

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Detalles Bibliográficos
Autores principales: Trentzsch, Marcus, Nyamugenda, Eugene, Miles, Tiffany K., Griffin, Haven, Russell, Susan, Koss, Brian, Cooney, Kimberly A., Phelan, Kevin D., Tackett, Alan J., Iyer, Srividhya, Boysen, Gunnar, Baldini, Giulia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7028721/
https://www.ncbi.nlm.nih.gov/pubmed/32123584
http://dx.doi.org/10.1038/s41420-020-0241-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7028721/
https://www.ncbi.nlm.nih.gov/pubmed/32123584
http://dx.doi.org/10.1038/s41420-020-0241-z

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