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Longitudinal changes in the frequency of mosaic chromosome Y loss in peripheral blood cells of aging men varies profoundly between individuals

Mosaic loss of chromosome Y (LOY) is the most common somatic genetic aberration and is associated with increased risk for all-cause mortality, various forms of cancer and Alzheimer’s disease, as well as other common human diseases. By tracking LOY frequencies in subjects from which blood samples hav...

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Detalles Bibliográficos
Autores principales: Danielsson, Marcus, Halvardson, Jonatan, Davies, Hanna, Torabi Moghadam, Behrooz, Mattisson, Jonas, Rychlicka-Buniowska, Edyta, Jaszczyński, Janusz, Heintz, Julia, Lannfelt, Lars, Giedraitis, Vilmantas, Ingelsson, Martin, Dumanski, Jan P., Forsberg, Lars A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7028735/
https://www.ncbi.nlm.nih.gov/pubmed/31654039
http://dx.doi.org/10.1038/s41431-019-0533-z