Cargando…
Longitudinal changes in the frequency of mosaic chromosome Y loss in peripheral blood cells of aging men varies profoundly between individuals
Mosaic loss of chromosome Y (LOY) is the most common somatic genetic aberration and is associated with increased risk for all-cause mortality, various forms of cancer and Alzheimer’s disease, as well as other common human diseases. By tracking LOY frequencies in subjects from which blood samples hav...
Autores principales: | Danielsson, Marcus, Halvardson, Jonatan, Davies, Hanna, Torabi Moghadam, Behrooz, Mattisson, Jonas, Rychlicka-Buniowska, Edyta, Jaszczyński, Janusz, Heintz, Julia, Lannfelt, Lars, Giedraitis, Vilmantas, Ingelsson, Martin, Dumanski, Jan P., Forsberg, Lars A. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7028735/ https://www.ncbi.nlm.nih.gov/pubmed/31654039 http://dx.doi.org/10.1038/s41431-019-0533-z |
Ejemplares similares
-
Loss of Y and clonal hematopoiesis in blood—two sides of the same coin?
por: Ljungström, Viktor, et al.
Publicado: (2021) -
Immune cells lacking Y chromosome show dysregulation of autosomal gene expression
por: Dumanski, Jan P., et al.
Publicado: (2021) -
Mosaic Loss of Chromosome Y in Blood Is Associated with Alzheimer Disease
por: Dumanski, Jan P., et al.
Publicado: (2016) -
Reply to Veitia
por: Danielsson, Marcus, et al.
Publicado: (2021) -
A polygenic risk score predicts mosaic loss of chromosome Y in circulating blood cells
por: Riaz, Moeen, et al.
Publicado: (2021)