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Intravitreal Delivery of Melatonin Is Protective Against the Photoreceptor Loss in Mice: A Potential Therapeutic Strategy for Degenerative Retinopathy

Melatonin is a circadian hormone with potent cytoprotective effects. Retinitis pigmentosa (RP) comprises a heterogeneous group of inherent retinopathies that characterized by the photoreceptor death in bilateral eyes. The N-methyl-N-nitrosourea (MNU) administered mouse is a type of chemically induce...

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Detalles Bibliográficos
Autores principales: Li, Chong, Tian, Yi, Yao, Anhui, Zha, Xiaobing, Zhang, Jianbin, Tao, Ye
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7028754/
https://www.ncbi.nlm.nih.gov/pubmed/32116667
http://dx.doi.org/10.3389/fphar.2019.01633