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Biopharmaceutical Understanding of Excipient Variability on Drug Apparent Solubility Based on Drug Physicochemical Properties: Case Study—Hypromellose (HPMC)

Identification of the biopharmaceutical risks of excipients and excipient variability on oral drug performance can be beneficial for the development of robust oral drug formulations. The current study investigated the impact of Hypromellose (HPMC) presence and varying viscosity type, when used as a...

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Detalles Bibliográficos
Autores principales: Zarmpi, P., Flanagan, T., Meehan, E., Mann, J., Fotaki, N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7028811/
https://www.ncbi.nlm.nih.gov/pubmed/32072317
http://dx.doi.org/10.1208/s12248-019-0411-1