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Mathematical modelling of telomere length dynamics

Telomeres are repetitive DNA sequences located at the ends of chromosomes. During cell division, an incomplete copy of each chromosome’s DNA is made, causing telomeres to shorten on successive generations. When a threshold length is reached replication ceases and the cell becomes ‘senescent’. In thi...

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Detalles Bibliográficos
Autores principales: Wattis, Jonathan A. D., Qi, Qi, Byrne, Helen M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7028829/
https://www.ncbi.nlm.nih.gov/pubmed/31728621
http://dx.doi.org/10.1007/s00285-019-01448-y