Bromodomain and extraterminal domain inhibitor enhances the antitumor effect of imatinib in gastrointestinal stromal tumours

In gastrointestinal stromal tumours (GISTs), the function of bromodomain‐containing 4 (BRD4) remains underexplored. BRD4 mRNA abundance was quantified in GISTs. In the current study, we investigated the role of BRD4 in GISTs. Our results show a significant enhancement in BRD4 mRNA and a shift from v...

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Detalles Bibliográficos
Autores principales: Mu, Jianfeng, Sun, Pengfei, Ma, Zhiming, Sun, Pengda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7028844/
https://www.ncbi.nlm.nih.gov/pubmed/31957165
http://dx.doi.org/10.1111/jcmm.14945

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7028844/
https://www.ncbi.nlm.nih.gov/pubmed/31957165
http://dx.doi.org/10.1111/jcmm.14945

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