PARP inhibitor Olaparib increases the sensitization to radiotherapy in FaDu cells

Radioresistance causes a major problem for improvement of outcomes of patients treated with radiation. Targeting for DNA repair deficient mechanisms is a hallmark of sensitization to resistance. We tested whether Olaparib, a (poly) ADP‐ribose polymerase (PARP) inhibitor, can sensitize the radioresis...

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Detalles Bibliográficos
Autores principales: Liu, Chuan, Gross, Neil, Li, Yanshi, Li, Guojun, Wang, Zhihai, Zhong, Shixun, Li, Yuncheng, Hu, Guohua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7028864/
https://www.ncbi.nlm.nih.gov/pubmed/31957270
http://dx.doi.org/10.1111/jcmm.14929

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7028864/
https://www.ncbi.nlm.nih.gov/pubmed/31957270
http://dx.doi.org/10.1111/jcmm.14929

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