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Bruceine D induces lung cancer cell apoptosis and autophagy via the ROS/MAPK signaling pathway in vitro and in vivo

Worldwide, lung cancer remains a leading cause of cancer mortality. Bruceine D (BD) has been shown to induce pancreatic cancer cell death via several different mechanisms. In this study, we demonstrated that BD inhibited lung cancer cell proliferation. Apoptosis and autophagy were the most important...

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Detalles Bibliográficos
Autores principales: Fan, Jiangjiang, Ren, Dongmei, Wang, Jinxia, Liu, Xiaoqing, Zhang, Huaran, Wu, Mingsheng, Yang, Guotao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7028916/
https://www.ncbi.nlm.nih.gov/pubmed/32071301
http://dx.doi.org/10.1038/s41419-020-2317-3