Cargando…

The effect of co-occurring lesions on leukaemogenesis and drug response in T-ALL and ETP-ALL

Despite advances in the management of acute lymphoblastic leukaemia (ALL), current regimens fail to significantly transform outcomes for patients with high-risk subtypes. Advances in genomic analyses have identified novel lesions including mutations in genes that encode chromatin modifiers and those...

Descripción completa

Detalles Bibliográficos
Autores principales: Tavakoli Shirazi, Paniz, Eadie, Laura N., Heatley, Susan L., Hughes, Timothy P., Yeung, David T., White, Deborah L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7028932/
https://www.ncbi.nlm.nih.gov/pubmed/31792348
http://dx.doi.org/10.1038/s41416-019-0647-7