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The effect of co-occurring lesions on leukaemogenesis and drug response in T-ALL and ETP-ALL
Despite advances in the management of acute lymphoblastic leukaemia (ALL), current regimens fail to significantly transform outcomes for patients with high-risk subtypes. Advances in genomic analyses have identified novel lesions including mutations in genes that encode chromatin modifiers and those...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7028932/ https://www.ncbi.nlm.nih.gov/pubmed/31792348 http://dx.doi.org/10.1038/s41416-019-0647-7 |