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A lncRNA-SWI/SNF complex crosstalk controls transcriptional activation at specific promoter regions

LncRNAs have been shown to be direct players in chromatin regulation, but little is known about their role at active genomic loci. We investigate the role of lncRNAs in gene activation by profiling the RNA interactome of SMARCB1-containing SWI/SNF complexes in proliferating and senescent conditions....

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Detalles Bibliográficos
Autores principales: Grossi, Elena, Raimondi, Ivan, Goñi, Enrique, González, Jovanna, Marchese, Francesco P., Chapaprieta, Vicente, Martín-Subero, José I., Guo, Shuling, Huarte, Maite
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7028943/
https://www.ncbi.nlm.nih.gov/pubmed/32071317
http://dx.doi.org/10.1038/s41467-020-14623-3