Genome-Wide Association Study of VKORC1 and CYP2C9 on acenocoumarol dose, stroke recurrence and intracranial haemorrhage in Spain

Acenocoumarol is an oral anticoagulant with significant interindividual dose variations. Variants in CYP2C9 and VKORC1 have been associated with acenocoumarol maintenance dose. We analysed whether any of the 49 polymorphisms in CYP2C9 and VKORC1 previously associated with acenocoumarol maintenance d...

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Detalles Bibliográficos
Autores principales: Cullell, Natalia, Carrera, Caty, Muiño, Elena, Torres-Aguila, Nuria-Paz, Cárcel-Márquez, Jara, González-Sánchez, Jonathan, Gallego-Fabrega, Cristina, Molina, Jessica, Besora, Sarah, Sotoca, Javier, Buongiorno, Maria-Teresa, Jiménez-Conde, Jordi, Giralt-Steinhauer, Eva, de Torres-Chacón, Reyes, Montaner, Joan, Mancha, Fernando, Cabezas, Juan A, Martí-Fàbregas, Joan, Prats-Sánchez, Luis, Camps-Renom, Pol, Purroy, Francisco, Cambray, Serafi, Freijo, María del Mar, Vives-Bauzá, Cristòfol, Tur, Silvia, Font, Maria-Àngels, López-Cancio, Elena, Hernandez-Perez, Maria, Obach, Victor, Calleja, Ana, Arenillas, Juan, Rodríguez-Yáñez, Manuel, Castillo, José, Sobrino, Tomas, Fernández-Cádenas, Israel, Krupinski, Jerzy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7028945/
https://www.ncbi.nlm.nih.gov/pubmed/32071341
http://dx.doi.org/10.1038/s41598-020-59641-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7028945/
https://www.ncbi.nlm.nih.gov/pubmed/32071341
http://dx.doi.org/10.1038/s41598-020-59641-9

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