A novel STAT3 inhibitor attenuates angiotensin II-induced abdominal aortic aneurysm progression in mice through modulating vascular inflammation and autophagy

Abdominal Aortic aneurysm (AAA) is associated with chronic inflammation, cells apoptosis, and impairment of autophagy. BP-1-102, a novel potent STAT3 inhibitor, has been recently reported to significantly block inflammation-related signaling pathways of JAK2/STAT3 and NF-κB, as well as regulate auto...

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Detalles Bibliográficos
Autores principales: Wu, Qi-ying, Cheng, Zhao, Zhou, Yang-zhao, Zhao, Yuan, Li, Jian-ming, Zhou, Xin-min, Peng, Hong-ling, Zhang, Guang-sheng, Liao, Xiao-bo, Fu, Xian-ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7028955/
https://www.ncbi.nlm.nih.gov/pubmed/32071300
http://dx.doi.org/10.1038/s41419-020-2326-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7028955/
https://www.ncbi.nlm.nih.gov/pubmed/32071300
http://dx.doi.org/10.1038/s41419-020-2326-2

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