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Novel biomarkers for risk stratification of Barrett’s oesophagus associated neoplastic progression–epithelial HMGB1 expression and stromal lymphocytic phenotype

BACKGROUND: The incidence of oesophageal adenocarcinoma is increasing globally. Barrett’s oesophagus (BO) is a pre-malignant condition with no biomarker to risk stratify those at highest risk of dysplasia and malignant transformation. METHODS: Subcellular epithelial protein (HMGB1, p53, RUNX3) expre...

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Detalles Bibliográficos
Autores principales: Porter, Ross J., Murray, Graeme I., Brice, Daniel P., Petty, Russell D., McLean, Mairi H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7028982/
https://www.ncbi.nlm.nih.gov/pubmed/31831860
http://dx.doi.org/10.1038/s41416-019-0685-1