Nongenic cancer-risk SNPs affect oncogenes, tumour-suppressor genes, and immune function

BACKGROUND: Genome-wide association studies (GWASes) have identified many noncoding germline single-nucleotide polymorphisms (SNPs) that are associated with an increased risk of developing cancer. However, how these SNPs affect cancer risk is still largely unknown. METHODS: We used a systems biology...

Descripción completa

Detalles Bibliográficos
Autores principales: Fagny, Maud, Platig, John, Kuijjer, Marieke Lydia, Lin, Xihong, Quackenbush, John
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7028992/
https://www.ncbi.nlm.nih.gov/pubmed/31806877
http://dx.doi.org/10.1038/s41416-019-0614-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7028992/
https://www.ncbi.nlm.nih.gov/pubmed/31806877
http://dx.doi.org/10.1038/s41416-019-0614-3

Ejemplares similares