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Nongenic cancer-risk SNPs affect oncogenes, tumour-suppressor genes, and immune function
BACKGROUND: Genome-wide association studies (GWASes) have identified many noncoding germline single-nucleotide polymorphisms (SNPs) that are associated with an increased risk of developing cancer. However, how these SNPs affect cancer risk is still largely unknown. METHODS: We used a systems biology...
Autores principales: | Fagny, Maud, Platig, John, Kuijjer, Marieke Lydia, Lin, Xihong, Quackenbush, John |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7028992/ https://www.ncbi.nlm.nih.gov/pubmed/31806877 http://dx.doi.org/10.1038/s41416-019-0614-3 |
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