Chromatin remodeling protein HELLS is critical for retinoblastoma tumor initiation and progression

Retinoblastoma is an aggressive childhood cancer of the developing retina that initiates by biallelic RB1 gene inactivation. Tumor progression in retinoblastoma is driven by epigenetics, as retinoblastoma genomes are stable, but the mechanism(s) that drive these epigenetic changes remain unknown. Ly...

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Detalles Bibliográficos
Autores principales: Zocchi, Loredana, Mehta, Aditi, Wu, Stephanie C., Wu, Jie, Gu, Yijun, Wang, Jingtian, Suh, Susie, Spitale, Robert C., Benavente, Claudia A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7028996/
https://www.ncbi.nlm.nih.gov/pubmed/32071286
http://dx.doi.org/10.1038/s41389-020-0210-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7028996/
https://www.ncbi.nlm.nih.gov/pubmed/32071286
http://dx.doi.org/10.1038/s41389-020-0210-7

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