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Upregulation of SMYD3 and SMYD3 VNTR 3/3 polymorphism increase the risk of hepatocellular carcinoma

SMYD3 (SET and MYND domain-containing protein 3) is involved in histone modification, which initiates oncogenesis by activating transcription of multiple downstream genes. To investigate associations of variable numbers of tandem repeats (VNTR) variants in the SMYD3 gene promoter, SMYD3 serum levels...

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Detalles Bibliográficos
Autores principales: Binh, Mai Thanh, Hoan, Nghiem Xuan, Giang, Dao Phuong, Tong, Hoang Van, Bock, C.-Thomas, Wedemeyer, Heiner, Toan, Nguyen Linh, Bang, Mai Hong, Kremsner, Peter G., Meyer, Christian G., Song, Le Huu, Velavan, Thirumalaisamy P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7029004/
https://www.ncbi.nlm.nih.gov/pubmed/32071406
http://dx.doi.org/10.1038/s41598-020-59667-z