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An Advanced Human Intestinal Coculture Model Reveals Compartmentalized Host and Pathogen Strategies during Salmonella Infection

A major obstacle in infection biology is the limited ability to recapitulate human disease trajectories in traditional cell culture and animal models, which impedes the translation of basic research into clinics. Here, we introduce a three-dimensional (3D) intestinal tissue model to study human ente...

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Detalles Bibliográficos
Autores principales: Schulte, Leon N., Schweinlin, Matthias, Westermann, Alexander J., Janga, Harshavardhan, Santos, Sara C., Appenzeller, Silke, Walles, Heike, Vogel, Jörg, Metzger, Marco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7029144/
https://www.ncbi.nlm.nih.gov/pubmed/32071273
http://dx.doi.org/10.1128/mBio.03348-19