Cargando…
An Advanced Human Intestinal Coculture Model Reveals Compartmentalized Host and Pathogen Strategies during Salmonella Infection
A major obstacle in infection biology is the limited ability to recapitulate human disease trajectories in traditional cell culture and animal models, which impedes the translation of basic research into clinics. Here, we introduce a three-dimensional (3D) intestinal tissue model to study human ente...
Autores principales: | Schulte, Leon N., Schweinlin, Matthias, Westermann, Alexander J., Janga, Harshavardhan, Santos, Sara C., Appenzeller, Silke, Walles, Heike, Vogel, Jörg, Metzger, Marco |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7029144/ https://www.ncbi.nlm.nih.gov/pubmed/32071273 http://dx.doi.org/10.1128/mBio.03348-19 |
Ejemplares similares
-
A three-dimensional intestinal tissue model reveals factors and small regulatory RNAs important for colonization with Campylobacter jejuni
por: Alzheimer, Mona, et al.
Publicado: (2020) -
Triple co-culture and perfusion bioreactor for studying the interaction between Neisseria gonorrhoeae and neutrophils: A novel 3D tissue model for bacterial infection and immunity
por: Heydarian, Motaharehsadat, et al.
Publicado: (2021) -
A primary cell-based in
vitro model of the human small intestine reveals host olfactomedin 4 induction in response to Salmonella Typhimurium infection
por: Däullary, Thomas, et al.
Publicado: (2023) -
Resolving host–pathogen interactions by dual RNA-seq
por: Westermann, Alexander J., et al.
Publicado: (2017) -
Biomimetic Human Tissue Model for Long-Term Study of Neisseria gonorrhoeae Infection
por: Heydarian, Motaharehsadat, et al.
Publicado: (2019)